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1

Synthesis, Binding, and Modeling Studies of New Cytisine Derivatives, as Ligands for Neuronal Nicotinic Acetylcholine Receptor Subtypes

Tasso, Bruno, Canu Boido, Caterina, Terranova, Emanuela, Gotti, Cecilia, Riganti, Loredana, Clementi, Francesco, Artali, Roberto, Bombieri, Gabriella, Meneghetti, Fiorella, Sparatore, Fabio

Journal:

Journal of Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 4.42 MB

english, 2009

2

The Influence of the Nitrogen Substitution in Three Cytisine Derivatives as Ligands for the Neuronal nAChRs: A Structural and Theoretical Study

Gabriella Bombieri, Fiorella Meneghetti, Roberto Artali, Bruno Tasso, Caterina Canu Boido, Fabio Sparatore

Journal:

Chemistry & Biodiversity

Année:

2008

Langue:

english

Fichier:

PDF, 440 KB

english, 2008

3

Organometallic compounds in oncology: implications of novel organotins as antitumor agents

Angela Alama, Bruno Tasso, Federica Novelli, Fabio Sparatore

Journal:

Drug Discovery Today

Année:

2009

Langue:

english

Fichier:

PDF, 599 KB

english, 2009

4

‘Selfies’ Reveal Systematic Deviations from Known Principles of Photographic Composition

Bruno, Nicola, Gabriele, Valentina, Bertamini, Marco, Tasso, Tiziana

Journal:

Art & Perception

Année:

2014

Langue:

english

Fichier:

PDF, 500 KB

english, 2014

5

Letter to the editor: “Indwelling central venous catheter-related sepsis”

Castagnola, Elio, Conte, Massimo, Garaventa, Alberto, Tasso, Loredana, De Bernardi, Bruno, Dini, Giorgio, Mori, Pier Giorgio, Massimo, Luisa

Journal:

Medical and Pediatric Oncology

Année:

1998

Langue:

english

Fichier:

PDF, 15 KB

english, 1998

6

Pharmacophoric pattern in valpromide derivatives

Silvina Tasso, Luis Bruno-Blanch, Guillermina L. Estiú

Journal:

International Journal of Quantum Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 170 KB

english, 1997

7

On the origin of the lack of anticonvulsant activity of some valpromide derivatives

S. M. Tasso, L. Bruno-Blanch, G. L. Estiú

Journal:

International Journal of Quantum Chemistry

Année:

1998

Langue:

english

Fichier:

PDF, 359 KB

english, 1998

8

Quinolizidinyl-benzimidazoles as Platelet-Antiaggregating Agents

Iana Vazzana, Emanuela Terranova, Bruno Tasso, Michele Tonelli, Antonietta Piana, Stefanella Gastaldi, Fabio Sparatore

Journal:

Chemistry & Biodiversity

Année:

2008

Langue:

english

Fichier:

PDF, 245 KB

english, 2008

9

ChemInform Abstract: Quinolizidinyl Derivatives of 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one as Ligands for Muscarinic Receptors.

Federica Novelli, Anna Sparatore, Bruno Tasso, Fabio Sparatore

Journal:

Année:

2000

Fichier:

PDF, 29 KB

2000

10

N-Homolupinanoyl and N-(ω-Lupinylthio)alkanoyl Derivatives of Some Tricyclic Systems as Ligands for Muscarinic M1 and M2 Receptor Subtypes.

Bruno Tasso, Anna Sparatore, Fabio Sparatore

Journal:

Année:

2004

Fichier:

PDF, 69 KB

2004

11

Epimerization of Lupinine to Epilupinine and vice versa. Reexamination of the Structures of Lupinal and Epilupinal

Anna Sparatore, Bruno Tasso, Vito Boido, Fabio Sparatore

Journal:

Helvetica Chimica Acta

Année:

2005

Langue:

english

Fichier:

PDF, 82 KB

english, 2005

12

Characterization of the anticonvulsant profile of valpromide derivatives

Silvina M Tasso, Sung Ch Moon, Luis E Bruno-Blanch, Guillermina L Estiú

Journal:

Bioorganic & Medicinal Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 508 KB

english, 2004

13

Quinolizidinyl derivatives of 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one as ligands for muscarinic receptors

Federica Novelli, Anna Sparatore, Bruno Tasso, Fabio Sparatore

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1999

Langue:

english

Fichier:

PDF, 229 KB

english, 1999

14

Pharmacophore model for antiepileptic drugs acting on sodium channels

Silvina M. Tasso, Luis E. Bruno-Blanch, Guillermina L. Estiú

Journal:

Journal of Molecular Modeling

Année:

2001

Langue:

english

Fichier:

PDF, 111 KB

english, 2001

15

In vitro cytotoxic activity of tri-n-butyltin(IV)lupinylsulfide hydrogen fumarate (IST-FS 35) and preliminary antitumor activity in vivo

Angela Alama, Maurizio Viale, Michele Cilli, Cristina Bruzzo, Federica Novelli, Bruno Tasso, Fabio Sparatore

Journal:

Investigational New Drugs

Année:

2009

Langue:

english

Fichier:

PDF, 165 KB

english, 2009

16

Efficacy of Novel Acridine Derivatives in the Inhibition of hPrP90-231 Prion Protein Fragment Toxicity

Valentina Villa, Michele Tonelli, Stefano Thellung, Alessandro Corsaro, Bruno Tasso, Federica Novelli, Caterina Canu, Albiana Pino, Katia Chiovitti, Domenico Paludi, Claudio Russo, Anna Sparatore, Ant

Journal:

Neurotoxicity Research

Année:

2011

Langue:

english

Fichier:

PDF, 680 KB

english, 2011

17

Antiviral and cytotoxic activities of aminoarylazo compounds and aryltriazene derivatives

Michele Tonelli, Iana Vazzana, Bruno Tasso, Vito Boido, Fabio Sparatore, Maurizio Fermeglia, Maria Silvia Paneni, Paola Posocco, Sabrina Pricl, Paolo La Colla, Cristina Ibba, Barbara Secci, Gabriella

Journal:

Bioorganic & Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 848 KB

english, 2009

18

Antiviral activity of benzimidazole derivatives. II. Antiviral activity of 2-phenylbenzimidazole derivatives

Michele Tonelli, Matteo Simone, Bruno Tasso, Federica Novelli, Vito Boido, Fabio Sparatore, Giuseppe Paglietti, Sabrina Pricl, Gabriele Giliberti, Sylvain Blois, Cristina Ibba, Giuseppina Sanna, Rober

Journal:

Bioorganic & Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 534 KB

english, 2010

19

Acridine derivatives as anti-BVDV agents

Michele Tonelli, Gerolamo Vettoretti, Bruno Tasso, Federica Novelli, Vito Boido, Fabio Sparatore, Bernardetta Busonera, Aicha Ouhtit, Pamela Farci, Sylvain Blois, Gabriele Giliberti, Paolo La Colla

Journal:

Antiviral Research

Année:

2011

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2011

20

Cytisine derivatives as ligands for neuronal nicotine receptors and with various pharmacological activities

Caterina Canu Boido, Bruno Tasso, Vito Boido, Fabio Sparatore

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 297 KB

english, 2003

21

N-Homolupinanoyl and N-(ω-lupinylthio)alkanoyl derivatives of some tricyclic systems as ligands for muscarinic M1 and M2 receptor subtypes

Bruno Tasso, Anna Sparatore, Fabio Sparatore

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 245 KB

english, 2003

22

Synthesis and pharmacological evaluation of some thiolupinine derivatives

Federica Novelli, Bruno Tasso, Fabio Sparatore

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 89 KB

english, 1999

23

Pharmacophore searching and QSAR analysis in the design of anticonvulsant drugs

S.M. Tasso, L.E. Bruno-Blanch, S.C. Moon, G.L. Estiú

Journal:

Journal of Molecular Structure: THEOCHEM

Année:

2000

Langue:

english

Fichier:

PDF, 383 KB

english, 2000

24

CC4, a dimer of cytisine, is a selective partial agonist at α4β2/α6β2 nAChR with improved selectivity for tobacco smoking cessation

Sala, Mariaelvina, Braida, Daniela, Pucci, Luca, Manfredi, Irene, Marks, Michael J, Wageman, Charles R, Grady, Sharon R, Loi, Barbara, Fucile, Sergio, Fasoli, Francesca, Zoli, Michele, Tasso, Bruno, S

Journal:

British Journal of Pharmacology

Année:

2013

Langue:

english

Fichier:

PDF, 2.51 MB

english, 2013

25

(+)-Laburnamine, a Natural Selective Ligand and Partial Agonist for the α4β2 Nicotinic Receptor Subtype

Tasso, Bruno, Novelli, Federica, Sparatore, Fabio, Fasoli, Francesca, Gotti, Cecilia

Journal:

Journal of Natural Products

Année:

2013

Langue:

english

Fichier:

PDF, 554 KB

english, 2013

26

Primary anti-proliferative activity evaluation of 1-(quinolizidin-1’-yl)methyl- and 1-((omega )-tert-amino)alkyl-substituted 2-phenyl-, 2-benzyl- and 2-[(benzotriazol-1/2-yl)methyl]benzimidazoles on human cancer cell lines

Tonelli, Michele, Tasso, Bruno, Mina, Lorenzo, Paglietti, Giuseppe, Boido, Vito, Sparatore, Fabio

Journal:

Molecular Diversity

Année:

2013

Langue:

english

Fichier:

PDF, 317 KB

english, 2013

27

Novel Quinolizidinyl Derivatives as Antiarrhythmic Agents: 2. Further Investigation

Tasso, Bruno, Budriesi, Roberta, Vazzana, Iana, Ioan, Pierfranco, Micucci, Matteo, Novelli, Federica, Tonelli, Michele, Sparatore, Anna, Chiarini, Alberto, Sparatore, Fabio

Journal:

Journal of Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2010

28

Short exposure of albumin to high concentrations of malondialdehyde does not mimic physiological conditions

Millanta, Susanna, Furfaro, Anna Lisa, Carlier, Paolo, Tasso, Bruno, Nitti, Mariapaola, Domenicotti, Cinzia, Odetti, Patrizio, Pronzato, Maria Adelaide, Traverso, Nicola

Journal:

Experimental and Molecular Pathology

Année:

2013

Langue:

english

Fichier:

PDF, 875 KB

english, 2013

29

Evaluation of neurotransmitter receptor gene expression identifies GABA receptor changes: A follow-up study in antipsychotic-naïve patients with first-episode psychosis

Ota, Vanessa Kiyomi, Noto, Cristiano, Gadelha, Ary, Santoro, Marcos Leite, Ortiz, Bruno Bertolucci, Andrade, Elvis Henrique, Tasso, Brazilio Carvalho, Spindola, Leticia Maria Nery, Silva, Patricia Nat

Journal:

Journal of Psychiatric Research

Année:

2014

Langue:

english

Fichier:

PDF, 521 KB

english, 2014

30

Antiviral activity of benzimidazole derivatives. III. Novel anti-CVB-5, anti-RSV and anti-Sb-1 agents

Tonelli, Michele, Novelli, Federica, Tasso, Bruno, Vazzana, Iana, Sparatore, Anna, Boido, Vito, Sparatore, Fabio, La Colla, Paolo, Sanna, Giuseppina, Giliberti, Gabriele, Busonera, Bernardetta, Farci,

Journal:

Bioorganic & Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2014

31

On the self-condensation of aminoguanidine leading to 1,1,4,10,10-pentaamino-2,3,5,6,8,9-hexaazadeca-1,3,5,7,9-pentaene (structure elucidation through X-ray powder diffraction)

Tasso, Bruno, Pirisino, Gerolamo, Novelli, Federica, Garzon, Davide, Fruttero, Roberta, Sparatore, Fabio, Colombo, Valentina, Sironi, Angelo

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 675 KB

english, 2014

32

Novel Quinolizidinyl Derivatives as Antiarrhythmic Agents

Vazzana, Iana, Budriesi, Roberta, Terranova, Emanuela, Ioan, Pierfranco, Ugenti, Maria Paola, Tasso, Bruno, Chiarini, Alberto, Sparatore, Fabio

Journal:

Journal of Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 136 KB

english, 2007

33

Antitubercular activity of quinolizidinyl/pyrrolizidinylalkyliminophenazines

Tonelli, Michele, Novelli, Federica, Tasso, Bruno, Sparatore, Anna, Boido, Vito, Sparatore, Fabio, Cannas, Sara, Molicotti, Paola, Zanetti, Stefania, Parapini, Silvia, Loddo, Roberta

Journal:

Bioorganic & Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 693 KB

english, 2014

34

High-risk human papillomaviruses in two different primary tumors in the same patient

Mânlio Tasso de Oliveira Mota,, Bonilha, Jane Lopes, Rosa, Bruno Miziara, de Arruda, José Germano Ferraz, Soares, Fernando Augusto, Vassallo, José, Calmon, Marilia Freitas, Rahal, Paula

Journal:

International Journal of Urology

Année:

2013

Langue:

english

Fichier:

PDF, 172 KB

english, 2013

35

Vitamin E-coated filter decreases levels of free 4-hydroxyl-2-nonenal during haemodialysis sessions

Odetti, Patrizio, Traverso, Nicola, Monacelli, Fiammetta, Menini, Stefano, Vazzana, Jana, Tasso, Bruno, Pronzato, Maria Adelaide, Robaudo, Cristina, Deferrari, Giacomo

Journal:

Free Radical Research

Année:

2006

Langue:

english

Fichier:

PDF, 146 KB

english, 2006

36

Celecoxib Inhibits Prion Protein 90-231-Mediated Pro-inflammatory Responses in Microglial Cells

Villa, Valentina, Thellung, Stefano, Corsaro, Alessandro, Novelli, Federica, Tasso, Bruno, Colucci-D’Amato, Luca, Gatta, Elena, Tonelli, Michele, Florio, Tullio

Journal:

Molecular Neurobiology

Année:

2016

Langue:

english

Fichier:

PDF, 1.93 MB

english, 2016

37

Multitarget Therapeutic Leads for Alzheimer’s Disease: Quinolizidinyl Derivatives of Bi- and Tricyclic Systems as Dual Inhibitors of Cholinesterases and β-Amyloid (Aβ) Aggregation

Tonelli, Michele, Catto, Marco, Tasso, Bruno, Novelli, Federica, Canu, Caterina, Iusco, Giovanna, Pisani, Leonardo, Stradis, Angelo De, Denora, Nunzio, Sparatore, Anna, Boido, Vito, Carotti, Angelo, S

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 818 KB

english, 2015

38

Antiviral activity of benzotriazole derivatives. 5-[4-(Benzotriazol-2-yl)phenoxy]-2,2-dimethylpentanoic acids potently and selectively inhibit Coxsackie Virus B5

Loddo, Roberta, Novelli, Federica, Sparatore, Anna, Tasso, Bruno, Tonelli, Michele, Boido, Vito, Sparatore, Fabio, Collu, Gabriella, Delogu, Ilenia, Giliberti, Gabriele, La Colla, Paolo

Journal:

Bioorganic & Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 890 KB

english, 2015

39

Synthesis and Antiplasmodial Activity of Novel Chloroquine Analogues with Bulky Basic Side Chains

Tasso, Bruno, Novelli, Federica, Tonelli, Michele, Barteselli, Anna, Basilico, Nicoletta, Parapini, Silvia, Taramelli, Donatella, Sparatore, Anna, Sparatore, Fabio

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 640 KB

english, 2015

40

Peri-implantitis: a complex condition with non-linear characteristics

Papantonopoulos, Georgios, Gogos, Christos, Housos, Efthymios, Bountis, Tassos, Loos, Bruno G.

Journal:

Journal of Clinical Periodontology

Année:

2015

Langue:

english

Fichier:

PDF, 978 KB

english, 2015

41

Comparative Study of Genotoxicity Induced by Six Different PBDEs

Pereira, Lílian Cristina, de Souza, Alecsandra Oliveira, Meireles, Gabriela, Bernardes, Mariana Furio Franco, Tasso, Maria Júlia, Bruno, Vítor, Dorta, Daniel Junqueira, de Oliveira, Danielle Palma

Journal:

Basic & Clinical Pharmacology & Toxicology

Année:

2016

Langue:

english

Fichier:

PDF, 211 KB

english, 2016

42

Prediction of individual implant bone levels and the existence of implant “phenotypes”

Papantonopoulos, Georgios, Gogos, Christos, Housos, Efthymios, Bountis, Tassos, Loos, Bruno G.

Journal:

Clinical Oral Implants Research

Année:

2016

Langue:

english

Fichier:

PDF, 731 KB

english, 2016

43

NOVEL CELECOXIB ANALOGUES INHIBIT GLIAL PRODUCTION OF PROSTAGLANDIN E2, NITRIC OXIDE, AND OXYGEN RADICALS REVERTING THE NEUROINFLAMMATORY RESPONSES INDUCED BY MISFOLDED PRION PROTEIN FRAGMENT 90-231 OR LIPOPOLYSACCHARIDE

Villa, Valentina, Thellung, Stefano, Bajetto, Adriana, Gatta, Elena, Robello, Mauro, Novelli, Federica, Tasso, Bruno, Tonelli, Michele, Florio, Tullio

Journal:

Pharmacological Research

Année:

2016

Langue:

english

Fichier:

PDF, 2.39 MB

english, 2016

44

New arylsparteine derivatives as positive inotropic drugs

Boido, Vito, Ercoli, Marcella, Tonelli, Michele, Novelli, Federica, Tasso, Bruno, Sparatore, Fabio, Cichero, Elena, Fossa, Paola, Dorigo, Paola, Froldi, Guglielmina

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 1.58 MB

english, 2017

45

Benzimidazole-based derivatives as privileged scaffold developed for the treatment of the RSV infection: a computational study exploring the potency and cytotoxicity profiles

Cichero, Elena, Tonelli, Michele, Novelli, Federica, Tasso, Bruno, Delogu, Ilenia, Loddo, Roberta, Bruno, Olga, Fossa, Paola

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 21.17 MB

english, 2017

46

Host dihydrofolate reductase (DHFR)-directed cycloguanil analogues endowed with activity against influenza virus and respiratory syncytial virus

Tonelli, Michele, Naesens, Lieve, Gazzarrini, Sabrina, Santucci, Matteo, Cichero, Elena, Tasso, Bruno, Moroni, Anna, Costi, Maria Paola, Loddo, Roberta

Journal:

European Journal of Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2017

47

Synthesis and biological evaluation of novel thiazole- VX-809 hybrid derivatives as F508del correctors by QSAR-based filtering tools

Liessi, Nara, Cichero, Elena, Pesce, Emanuela, Arkel, Maria, Salis, Annalisa, Tomati, Valeria, Paccagnella, Matteo, Damonte, Gianluca, Tasso, Bruno, Galietta, Luis J.V., Pedemonte, Nicoletta, Fossa, P

Journal:

European Journal of Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 6.87 MB

english, 2017

48

Benzimidazole derivatives endowed with potent antileishmanial activity

Tonelli, Michele, Gabriele, Elena, Piazza, Francesca, Basilico, Nicoletta, Parapini, Silvia, Tasso, Bruno, Loddo, Roberta, Sparatore, Fabio, Sparatore, Anna

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 3.10 MB

english, 2018

49

Schneider’s first-rank symptoms as predictors of remission in antipsychotic-naive first-episode psychosis

Malinowski, Fernando R., Tasso, Brazilio de C., Ortiz, Bruno B., Higuchi, Cinthia H., Noto, Cristiano, Belangero, Sintia I., Bressan, Rodrigo A., Gadelha, Ary, Cordeiro, Quirino

Journal:

Revista Brasileira de Psiquiatria

Année:

2019

Langue:

english

Fichier:

PDF, 85 KB

english, 2019

50

Differential modulation of SIRT6 deacetylase and deacylase activities by lysine-based small molecules

Sociali, Giovanna, Liessi, Nara, Grozio, Alessia, Caffa, Irene, Parenti, Marco Daniele, Ravera, Silvia, Tasso, Bruno, Benzi, Andrea, Nencioni, Alessio, Del Rio, Alberto, Robina, Inmaculada, Millo, Enr

Journal:

Molecular Diversity

Année:

2019

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2019